Researchers at the University of California have discovered how the circadian clock affects cell growth, metabolism, and tumor progression.
In today’s world, there is an alarming increase in the incidence of cancer at a young age, including colorectal cancer (colon cancer). The underlying cause of this increased incidence of cancer in adults between the ages of 20 and 30 remains unclear. Suspected risk factors include aspects of the environment, such as lifestyle and dietary factors known to affect the circadian clock.
We are exposed daily to several environmental factors that affect our internal biological clock. These factors include night shift work, prolonged exposure to light, disturbances in sleep/wake cycles, and altered eating behavior. Social jetlag is one of the common phenomena of modern life.
Scientists believe that such disturbances in circadian rhythm play an important role in provoking cancer pathologies. The results of a new study indicate that disruption of circadian rhythms causes additional genomic mutations that are crucial in accelerating the development of colorectal cancer.
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